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Robert W Tuman Selected Research

PDGF receptor tyrosine kinase

12/2005(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: platelet-derived growth factor receptor tyrosine kinase inhibitors with broad antiproliferative activity against tumor cells.
8/2005Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis.

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Robert W Tuman Research Topics

Disease

3Neoplasms (Cancer)
11/2009 - 08/2005
1Adenocarcinoma of Lung
11/2009
1Neoplasm Metastasis (Metastasis)
11/2009
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2009
1Carcinoma (Carcinomatosis)
11/2009
1Colonic Neoplasms (Colon Cancer)
08/2005

Drug/Important Bio-Agent (IBA)

2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
11/2009 - 12/2005
2Phosphotransferases (Kinase)IBA
11/2009 - 12/2005
2PDGF receptor tyrosine kinaseIBA
12/2005 - 08/2005
1tyrosine receptor (receptor, tyrosine)IBA
11/2009
14- cyano- N- (2- (1- cyclohexen- 1- yl)- 4- (1- ((dimethylamino)acetyl)- 4- piperidinyl)phenyl)- 1H- imidazole- 2- carboxamideIBA
11/2009
1Zoledronic Acid (Zometa)FDA Link
11/2009
1Biomarkers (Surrogate Marker)IBA
11/2009
1Macrophage Colony-Stimulating FactorIBA
11/2009
1Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA
11/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2009
1Becaplermin (PDGF-BB)FDA Link
12/2005
1Aniline CompoundsIBA
12/2005
1AntibodiesIBA
08/2005
1(6,7- dimethoxy- 2,4- dihydroindeno(1,2- c)pyrazol- 3- yl)(3- fluorophenyl)amineIBA
08/2005
1Phospholipases (Phospholipase)IBA
08/2005